I have never consistently used Osmosis so I can't speak intelligently on their products (but I have liked what little I have used) but Rezenerate is amazing! Definitely worth the investment.
See below link for an earlier discussion about it on this site:
Thanks for your feedback Faye! Do you mind telling me what you charge per treatment and how many you recommend? Also, do you like a particular serum with the device?
Hi Faye! I got the Rezenerate last month and I'm just getting into it. Haven't totally fallen in love yet, but I'm doing a promo to get clients to try it and hopefully get more into it. Do you have any favorite combos, like microderm or dermaplaning before it? Also, do you use it on acne clients? and what serums do you like use for acne clients?